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Subunit: Directly interacts with F-actin and ABRA Sequence caution: Sequence=BAA74866.2; Type=Erroneous initiation; 2 PDB 3D structures from [IMAGE] and Proteopedia [IMAGE] for ABLIM3: 1UJS (3D) [IMAGE] 2DJ7 (3D) [IMAGE]
Tissue specificity: Expressed predominantly in heart and brain [IMAGE] Custom PCR Arrays for ABLIM3 Primer Products: [IMAGE] OriGene qSTAR qPCR primer pairs in human, mouse for ABLIM3 [IMAGE] Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ABLIM3 [IMAGE] QuantiTect
Function: UniProtKB/Swiss-Prot Summary: ABLM3_HUMAN, O94929 Function: May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity Gene Ontology (GO): 2 molecular function terms: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0003779 actin binding IEA -- GO:0008270 zinc ion binding IEA -- [IMAGE] Find genes that share ontologies with ABLIM3 About GenesLikeMe Phenotypes: 1 GenomeRNAi human phenotype for ABLIM3: Increased 8N DNA content Animal Models: [IMAGE] inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ABLIM3 [IMAGE] inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ABLIM3 [IMAGE] genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ABLIM3 [IMAGE] genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ABLIM3 miRNA Products: [IMAGE] Block miRNA regulation of human, mouse, rat ABLIM3 using miScript Target Protectors [IMAGE] Selected qRT-PCR Assays for microRNAs that regulate ABLIM3 (see all 28): hsa-miR-3685 hsa-miR-4311 hsa-miR-188-5p hsa-miR-3660 hsa-miR-605 hsa-miR-548s hsa-miR-410 hsa-miR-508-3p [IMAGE] SwitchGear 3'UTR luciferase reporter plasmid: ABLIM3 3' UTR sequence Inhib. RNA Products: [IMAGE] OriGene RNAi products in human, mouse, rat for ABLIM3 [IMAGE] Predesigned siRNA for gene silencing in human, mouse, rat ABLIM3 Gene Editing Products: [IMAGE] DNA2.0 Custom Protein Engineering Service for ABLIM3 Clone Products: [IMAGE] OriGene clones in human, mouse for ABLIM3 (see all 9) OriGene ORF clones in mouse, rat for ABLIM3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling [IMAGE] GenScript: all cDNA clones in your preferred vector: ABLIM3 (NM_014945) [IMAGE] Browse Sino Biological Human cDNA Clones [IMAGE] DNA2.0 Custom Codon Optimized Gene Synthesis Service for ABLIM3 [IMAGE] Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ABLIM3 Cell Line Products: [IMAGE] GenScript Custom overexpressing Cell Line Services for ABLIM3 [IMAGE] Browse ESI BIO Cell Lines and PureStem Progenitors for ABLIM3 [IMAGE] In Situ Assay Products: [IMAGE] Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ABLIM3
Similarity: Contains 1 HP (headpiece) domain Contains 4 LIM zinc-binding domains [IMAGE]
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