Gene content    
ANP32B ( by HUGO)
Acidic (Leucine-Rich) Nuclear Phosphoprotein 32 Family,...
Other
Acidic (Leucine-Rich) Nuclear Phosphoprotein 32 Family
Member B
Acidic Protein Rich In Leucines
Putative HLA-DR-Associated Protein I-2
Silver-Stainable Protein SSP29
APRIL
PHAPI2
SSP29
Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member B
NCBI: 9q22.32    Ensembl: 9q22.33
AN32B_HUMANSize: 251 amino acidsMass: 28788 Da

  • Subunit: Monomer. Interacts with histones H3 and H4 2 PDB 3D structures from [IMAGE] and Proteopedia [IMAGE] for ANP32B: 2ELL (3D) [IMAGE] 2RR6 (3D) [IMAGE]
  • Tissue specificity: Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta [IMAGE] Custom PCR Arrays for ANP32B Primer Products: [IMAGE] OriGene qPCR primer pairs and template standards for ANP32B OriGene qSTAR qPCR primer pairs in human, mouse for A
  • Function:
    UniProtKB/Swiss-Prot Summary: AN32B_HUMAN, Q92688 Function: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome Gene Ontology (GO): 2 molecular function terms: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0042393 histone binding IDA -- GO:0070063 RNA polymerase binding IDA 9285060 [IMAGE] Find genes that share ontologies with ANP32B About GenesLikeMe Phenotypes:
  • Similarity:
    Belongs to the ANP32 family
                          
    Contains 4 LRR (leucine-rich) repeats
                          
    Contains 1 LRRCT domain [IMAGE]

    • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR001611Leu-rich_rptLeucine-rich repeatRepeat
    IPR003603U2A'_phosphoprotein32A_CLeucine-rich-associatedDomain
    BlocksIPB003603Leucine-rich-associatedLeucine-rich-associated

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process positive regulation of protein export from nucleus IMP GOA 17178712
    Cellular Component colocalizes_with nucleolus IDA GOA 9285060
    cytoplasm IDA GOA 17178712
    nucleus IDA GOA 17178712
    Molecular Function RNA polymerase binding IDA GOA 9285060

    ANP32B cross reference    
    PubMed Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene