Gene content    
ANXA8 ( by HUGO)
Annexin A8
Other
Annexin A8
ANX8
Annexin VIII
Vascular Anticoagulant-Beta
VAC-beta
annexin-8
Annexin-8
NCBI: 10q11.22    Ensembl: 10q11.22
ANXA8_HUMANSize: 327 amino acidsMass: 36881 Da

  • Function:
    UniProtKB/Swiss-Prot Summary: ANXA8_HUMAN, P13928 Function: This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade
  • Similarity:
    Belongs to the annexin family
                          
    Contains 4 annexin repeats [IMAGE]

    • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR001464AnnexinAnnexinFamily
    IPR009115AnnexinVIIIAnnexin, type VIIIFamily
    BlocksIPB001464AnnexinAnnexin
    IPB002392Annexin type V signatureAnnexin type V signature

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process endosomal transport IMP GOA 18923148
    endosome organization IMP GOA 18923148
    Cellular Component cytosol IDA GOA 18923148
    late endosome membrane IDA GOA 18923148
    plasma membrane IDA GOA 18923148
    Molecular Function actin filament binding IDA GOA 16638567
    calcium ion binding IDA GOA 15644210
    calcium-dependent phospholipid binding IDA GOA 16638567
    phosphatidylinositol-3,4,5-trisphosphate binding IDA GOA 16638567
    phosphatidylinositol-3,4-bisphosphate binding IDA GOA 16638567
    phosphatidylinositol-4,5-bisphosphate binding IDA GOA 16638567

    ANXA8 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene