Gene content
Symbol	ARHGEF5 ( by HUGO)
Name	Rho Guanine Nucleotide Exchange Factor (GEF) 5
Category	Oncogene
Alias	Rho Guanine Nucleotide Exchange Factor (GEF) 5 Guanine Nucleotide Regulatory Protein TIM Transforming Immortalized Mammary Oncogene TIM Oncogene TIM P60 TIM GEF5 P60 TIM1 ephexin-3 Rho Guanine Nucleotide Exchange Factor 5 Ephexin-3
Cytogenetic band	NCBI: 7q35    Ensembl: 7q35
Protein information	ARHG5_HUMAN Size: 1597 amino acids Mass: 176799 Da Tissue specificity: Mainly expressed in kidney, liver, pancreas, lung and placenta [IMAGE] Custom PCR Arrays for ARHGEF5 Primer Products: [IMAGE] OriGene qSTAR qPCR primer pairs in human, mouse for ARHGEF5 [IMAGE] Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ARH Similarity: Contains 1 DH (DBL-homology) domain                        Contains 1 PH domain                        Contains 1 SH3 domain [IMAGE]

Protein Domain/Family
Source	ID	Domain	Name	Type
InterPro	IPR000219	DH-domain	DH	Domain
	IPR001331	GDS_CDC24_CS	Guanine-nucleotide dissociation stimulator, CDC24	Domain
	IPR001452	SH3_domain	SH3	Domain
	IPR001849	Pleckstrin_homology	Pleckstrin-like	Domain
	IPR011993	PH_like_dom	Pleckstrin homology-type	Domain
Blocks	IPB000219	DH domain	DH domain
	IPB001452	SH3 domain signature	SH3 domain signature
	IPB001849	Pleckstrin-like	Pleckstrin-like
	IPB011511	Variant SH3	Variant SH3

Gene Ontology
Type	Term	Evidence	Source	Pub
Molecular Function	GTP binding	TAS	GOA	8134109

ARHGEF5 cross reference
PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene