TAG for BAI2

Gene content

Symbol

BAI2 ( by HUGO)

Name

Brain-Specific Angiogenesis Inhibitor

Category

Tumor suppressor gene

Alias

Brain-Specific Angiogenesis Inhibitor 2
Brain-Specific Angiongenesis Inhibitor-2

Cytogenetic band

NCBI: 1p35 Ensembl: 1p35.2

Protein information

BAI2_HUMAN

Size: 1585 amino acids

Mass: 172656 Da

Subunit: Interacts with GABPB2 (By similarity) Sequence caution: Sequence=BAA25362.1; Type=Erroneous initiation; Sequence=CAI16890.1; Type=Erroneous gene model prediction;

Tissue specificity: Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines [IMAGE] Pathway & Disease-focused RT2 Profiler PCR Array including BAI2: G Protein Coupled Receptors 384HT in human mouse rat Primer Products: [IMAGE] O

Function:

UniProtKB/Swiss-Prot Summary: BAI2_HUMAN, O60241 Function: Might be involved in angiogenesis inhibition

Similarity:

Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily

Contains 1 GPS domain

Contains 4 TSP type-1 domains [IMAGE]

Protein Domain/Family
Source	ID	Domain	Name	Type
InterPro	IPR000203	GPS	GPS	Domain
	IPR000832	GPCR_2_secretin-like	GPCR, family 2, secretin-like	Family
	IPR000884	Thrombospondin_1_rpt	Thrombospondin, type I	Repeat
	IPR001879	GPCR_2_extracellular_dom	Hormone receptor, extracellular	Domain
	IPR008077	GPCR_2_brain-spec_angio_inhib	Brain-specific angiogenesis inhibitor	Family
Blocks	IPB000203	GPS domain	GPS domain
	IPB000832	G-protein coupled receptors family 2 (secretin-like)	G-protein coupled receptors family 2 (secretin-like)
	IPB000832	G-protein coupled receptors family 2 (secretin-like)	G-protein coupled receptors family 2 (secretin-like)
	IPB000832	G-protein coupled receptors family 2 (secretin-like) IPB000884 Thrombospondin IPB008085 Thrombospondin type 1 repeat signature	G-protein coupled receptors family 2 (secretin-like)
	IPB008077	Brain-specific angiogenesis inhibitor precursor signature	Brain-specific angiogenesis inhibitor precursor signature

Gene Ontology
Type	Term	Evidence	Source	Pub
Biological Process	G-protein coupled receptor signaling pathway	TAS	GOA	15203201

BAI2 cross reference