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Subunit: Interacts with TFCOUP1, PIAS3, ARP1 and EAR2 (By similarity) Sequence caution: Sequence=BAB47438.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Tissue specificity: Expressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes and megakaryocytes. Expression is tightly regulated during B-cell development [IMAGE] Custom PCR Arrays for BC
Function: UniProtKB/Swiss-Prot Summary: BC11A_HUMAN, Q9H165 Function: Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity) Gene Ontology (GO): 5 molecular function terms: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0003676 nucleic acid binding IEA -- GO:0003714 transcription corepressor activity IEA -- GO:0042803 protein homodimerization activity TAS 19616629 GO:0046872 metal ion binding IEA -- GO:0046982 protein heterodimerization activity IPI 19616629 [IMAGE] Find genes that share ontologies with BCL11A About GenesLikeMe Phenotypes:
Similarity: Contains 6 C2H2-type zinc fingers [IMAGE]
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