Gene content    
BCL7A ( by HUGO)
B-Cell CLL/Lymphoma 7A
Other
B-Cell CLL/Lymphoma 7A
BCL7
B-Cell CLL/Lymphoma 7 Protein Family Member A
B-Cell CLL/Lymphoma-7
NCBI: 12q24.13    Ensembl: 12q24.31
BCL7A_HUMANSize: 210 amino acidsMass: 22810 Da

  • Function:
    Genatlas biochemistry entry for BCL7A: putative F-actin cross-linking protein 12,homolog to caldesmon,involved with MYC and IGH in a Burkitt lymphoma cell line with complex translocation t(9;14;12)(q24.1;q32.3;q24.1) Gene Ontology (GO): 1 molecular function term: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0003674 molecular_function ND -- [IMAGE] Find genes that share ontologies with BCL7A About GenesLikeMe Phenotypes: 1 GenomeRNAi human phenotype for BCL7A: Increased gamma-H2AX phosphory Animal Models: [IMAGE] inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BCL7A [IMAGE] inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for BCL7A [IMAGE] genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BCL7A [IMAGE] genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for BCL7A miRNA Products: miRTarBase miRNAs that target BCL7A: hsa-let-7b-5p (MIRT002399), hsa-mir-29a-3p (MIRT006552), hsa-mir-24-3p (MIRT050374), hsa-mir-335-5p (MIRT017268) [IMAGE] Block miRNA regulation of human, mouse, rat BCL7A using miScript Target Protectors [IMAGE] Selected qRT-PCR Assays for microRNAs that regulate BCL7A (see all 99): hsa-miR-520e hsa-miR-3194-5p hsa-miR-15a hsa-miR-519a hsa-miR-502-3p hsa-miR-1244 hsa-miR-4325 hsa-miR-376a* [IMAGE] SwitchGear 3'UTR luciferase reporter plasmid: BCL7A 3' UTR sequence Inhib. RNA Products: [IMAGE] OriGene RNAi products in human, mouse, rat for BCL7A [IMAGE] Predesigned siRNA for gene silencing in human, mouse, rat BCL7A Gene Editing Products: [IMAGE] DNA2.0 Custom Protein Engineering Service for BCL7A Clone Products: [IMAGE] OriGene clones in human, mouse for BCL7A (see all 11) OriGene ORF clones in mouse, rat for BCL7A OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling [IMAGE] GenScript: all cDNA clones in your preferred vector (see all 2): BCL7A (NM_020993) [IMAGE] Browse Sino Biological Human cDNA Clones [IMAGE] DNA2.0 Custom Codon Optimized Gene Synthesis Service for BCL7A [IMAGE] Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BCL7A Cell Line Products: [IMAGE] GenScript Custom overexpressing Cell Line Services for BCL7A [IMAGE] Browse ESI BIO Cell Lines and PureStem Progenitors for BCL7A [IMAGE] In Situ Assay Products: [IMAGE] Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCL7A
  • Similarity:
    Belongs to the BCL7 family [IMAGE]
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR006804BCL7BCL7, N-terminalDomain

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process negative regulation of transcription, DNA-templated NAS GOA 15897551

    Disorder & Mutation    
    Source Disease
    SWISS-PROTNote=Chromosomal aberrations involving BCL7A may be a cause of B-cell non-Hodgkin lymphoma. Three-way translocation t(8;14;12)(q24.1;q32.3;q24.1) with MYC and with immunoglobulin gene regions

    BCL7A cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene