Gene content    
C13ORF15 (approved by HUGO)
chromosome 13 open reading frame 15
Other & Tumor suppressor gene
chromosome
13
open
reading
frame
151
KIAA05642
RGC-321
response
gene
to
complement
32
protein2
bA157L14.21
MGC873382
RGC321
NCBI: 13q14.11    Ensembl: 13q14.11
RGC32_HUMANSize: 137 amino acidsMass: 14559 Da

  • Subcellular location: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, centrosome. Note=Cytoplasmic in unstimulated cells. Nuclear after activation by complement. Associated with the centrosome during prometaphase and metaphase Secondary accessions: Q6NZ48 Q9UL69 Alternative splic
  • Subunit: Interacts with CDK1 and PLK1
  • Tissue specificity: Detected in brain, heart and liver (at protein level). Highly expressed in liver, skeletal muscle, kidney and pancreas. Detected at lower levels in heart, brain and placenta. Detected in aorta endothelial cells Primers: "" Origene genome-wide validated SY
  • Function:
    Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition
  • Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process cell cycle IEA GOA
    regulation of cyclin-dependent protein kinase activity TAS GOA 9756947
    Cellular Component cytoplasm IEA GOA
    cytoskeleton IEA GOA
    microtubule organizing center IEA GOA
    nucleus IEA GOA
    Molecular Function protein binding IEA GOA

    C13ORF15 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene