Gene content
Symbol	CCNDBP1 ( by HUGO)
Name	Cyclin D-Type Binding-Protein 1
Category	Tumor suppressor gene
Alias	Cyclin D-Type Binding-Protein 1 GCIP D-Type Cyclin-Interacting Protein 1 Grap2 And Cyclin-D-Interacting Protein Human Homolog Of Maid DIP1 HHM Grap2 Cyclin Interacting Protein HHM Protein MAID Protein Cyclin-D1-Binding Protein 1
Cytogenetic band	NCBI: 15q14-q15    Ensembl: 15q15.2
Protein information	CCDB1_HUMAN Size: 360 amino acids Mass: 40262 Da Subunit: Interacts with CCND1 and GRAP2. May also interact with COPS5, RPLP0, SIRT6, SYF2 and TCF3 Developmental stage: Expression may increase during differentiation Sequence caution: Sequence=AAD11777.1; Type=Frameshift; Positions=8, 14, 18; Sequence=AAP97163.1; Type=Frameshift; Positions=17, 40; 1 PDB 3D structure from [IMAGE] and Proteopedia [IMAGE] for CCNDBP1: 3AY5 (3D) [IMAGE] Tissue specificity: Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas [IMAGE] Custom PCR Arrays for CCNDBP1 Primer Products: [IMAGE] OriGene Function: UniProtKB/Swiss-Prot Summary: CCDB1_HUMAN, O95273 Function: May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription Similarity: Belongs to the CCNDBP1 family [IMAGE]

Gene Ontology
Type	Term	Evidence	Source	Pub
Molecular Function	protein binding	IPI	GOA	10915743

CCNDBP1 cross reference
PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene