Gene content    
CDK2AP1 ( by HUGO)
Cyclin-Dependent Kinase
Tumor suppressor gene
Cyclin-Dependent Kinase 2 Associated Protein 1
CDK2-Associated Protein 1
DOC1
Deleted In Oral Cancer 1
Putative Oral Cancer Suppressor
DORC1
ST19
Cyclin-Dependent Kinase 2-Associated Protein 1
Deleted In Oral Cancer-1
doc-1
p12DOC-1
CDKAP1
DOC-1
NCBI: 12q24.31    Ensembl: 12q24.31
CDKA1_HUMANSize: 115 amino acidsMass: 12365 Da

  • Subunit: Homodimer. Interacts with monomeric unphosphorylated CDK2 1 PDB 3D structure from [IMAGE] and Proteopedia [IMAGE] for CDK2AP1: 2KW6 (3D) [IMAGE]
  • Function:
    UniProtKB/Swiss-Prot Summary: CDKA1_HUMAN, O14519 Function: specific inhibitor of the cell-cycle kinase CDK2 (By similarity) Gene Ontology (GO): 1 molecular function term: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0003677 DNA binding TAS 9506968 [IMAGE] Find genes that share ontologies with CDK2AP1 About GenesLikeMe Phenotypes: 2 GenomeRNAi human phenotypes for CDK2AP1: Decreased viability with cispl Upregulation of Wnt/beta-caten
  • Similarity:
    Belongs to the CDK2AP family [IMAGE]
  • Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process DNA-dependent DNA replication NAS GOA 9506968
    positive regulation of protein phosphorylation IDA GOA 9506968
    Cellular Component nucleus IDA GOA 9506968
    perinuclear region of cytoplasm IDA GOA 9506968
    Molecular Function DNA polymerase binding IPI GOA 9506968

    CDK2AP1 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene