Gene content    
CHD1 (-- by HUGO)
chromodomain helicase DNA binding protein 1 CHD1: Approved
--
EC 3.6.4.12
chromodomain
helicase
DNA
binding
protein
CHD-1
ATP-dependent
helicase
CHD1
chromodomain-helicase-DNA-binding
protein
EC
NCBI: 5q15-q21    Ensembl: 5q21.1
CHD1_HUMANSize: 1710 amino acidsMass: 196688 Da

  • Subcellular location: Nucleus. Cytoplasm (By similarity). Note=Is released into the cytoplasm when cells enter mitosis and is reincorporated into chromatin during telophase-cytokinesis (By similarity) PDB 3D structures from [IMAGE] and Proteopedia [IMAGE] : 2B2T (3D) [IMAGE] 2
  • Subunit: Component of the SAGA complex (By similarity). Interacts with BCLAF1, NCoR, SRP20 and SAFB (By similarity). Specifically interacts with methylated H3K4me2 and H3K4me3. Interacts with the FACT complex, the PAF complex and the U2 snRNP. Interacts directly with PAF1, SFA3A1, SFA3A2, SFA3A3, SNF2 and SSRP1
  • Similarity:
    Belongs to the SNF2/RAD54 helicase family
                          
    Contains 2 chromo domains
                          
    Contains 1 helicase ATP-binding domain
                          
    Contains 1 helicase C-terminal domain

    • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR000330SNF2_NSNF2-relatedDomain
    IPR000953Chromo_domain/shadowChromoDomain
    BlocksIPB000330SNF2 related domainSNF2 related domain
    IPB001005Myb DNA-binding domainMyb DNA-binding domain
    IPB002464ATP-dependent helicaseATP-dependent helicase, DEAH-box

    CHD1 cross reference    
    PubMed Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene