Gene content    
CHRM5 ( by HUGO)
Cholinergic Receptor, Muscarinic 5
Other
Cholinergic Receptor
Muscarinic 5
Acetylcholine Receptor
Muscarinic 5
HM5
Acetylcholine Receptor
Muscarinic 5
Muscarinic Acetylcholine Receptor M5
NCBI: 15q26    Ensembl: 15q14
ACM5_HUMANSize: 532 amino acidsMass: 60074 Da

  • Function:
    UniProtKB/Swiss-Prot Summary: ACM5_HUMAN, P08912 Function: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover
  • Similarity:
    Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily [IMAGE]

    • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR000276GPCR_RhodpsnRhodopsin-like GPCR superfamilyFamily
    IPR000502Musac_Ach_M5_rcptMuscarinic acetylcholine receptor M5Family
    IPR000995Musac_Ach_rcptMuscarinic acetylcholine receptorFamily
    BlocksIPB000502Muscarinic M5 receptor signatureMuscarinic M5 receptor signature
    IPB000995Muscarinic acetylcholine receptor signatureMuscarinic acetylcholine receptor signature

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway TAS GOA 8663391
    cell proliferation TAS GOA 8063729
    G-protein coupled acetylcholine receptor signaling pathway TAS GOA 3272174
    metabolic process TAS GOA 1905013
    Molecular Function phosphatidylinositol phospholipase C activity TAS GOA 1905013

    CHRM5 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene