Gene content    
CTSZ ( by HUGO)
Cathepsin Z
Other
Cathepsin Z
Cathepsin X
Carboxypeptidase LB
Cathepsin B2
Cathepsin IV
Cathepsin Y
Cathepsin Z1
Cysteine-Type Carboxypeptidase
Lysosomal Carboxypeptidase B
Cathepsin P
EC 3.4.18.1
CTSX
Preprocathepsin P
NCBI: 20q13.32    Ensembl: 20q13.32
CATZ_HUMANSize: 303 amino acidsMass: 33868 Da

  • Tissue specificity: Widely expressed [IMAGE] Custom PCR Arrays for CTSZ Primer Products: [IMAGE] OriGene qPCR primer pairs and template standards for CTSZ OriGene qSTAR qPCR primer pairs in human, mouse for CTSZ [IMAGE] Pre-validated RT2 qPCR Primer Assay in human, mouse, ra
  • Function:
    Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity
                          
    Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity
  • Catalytic activity:
    Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity
  • Similarity:
    Belongs to the peptidase C1 family [IMAGE]
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR000668Peptidase_C1A_CPeptidase C1A, papainFamily
    BlocksIPB000668Papain cysteine protease (C1) family signaturePapain cysteine protease (C1) family signature

    CTSZ cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene