Gene content    
DHX16 ( by HUGO)
DEAH (Asp-Glu-Ala-His) Box Polypeptide 16
Other
DEAH (Asp-Glu-Ala-His) Box Polypeptide 16
DDX16
DBP2
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 16
ATP-Dependent RNA Helicase #3
DEAH-Box Protein 16
PRP8
PRO2014
PRPF2
Prp2
DEAD/H Box 16
Putative Pre-MRNA-Splicing Factor ATP-Dependent RNA Helicase DHX16
RNA Helicase
EC 3.6.4.13
KIAA0577
EC 3.6.1
NCBI: 6p21.3    Ensembl: 6p21.33
DHX16_HUMANSize: 1041 amino acidsMass: 119264 Da

  • Function:
    Probable ATP-binding RNA helicase involved in pre-mRNA splicing
                          
    Probable ATP-binding RNA helicase involved in pre-mRNA splicing
  • Catalytic activity:
    ATP + H(2)O = ADP + phosphate Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131 Gene Ontology (GO): Selected molecular function terms (see all 7): About this table GO ID Qualified GO term Evidence PubMed IDs GO:0003676 nucleic acid binding -- -- GO:0003724 RNA helicase activity TAS 9547260 GO:0004386 helicase activity -- -- GO:0005515 protein binding IPI -- GO:0005524 ATP binding IEA -- [IMAGE] Find genes that share ontologies with DHX16 About GenesLikeMe Animal Models: [IMAGE] inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DHX16 [IMAGE] inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DHX16 [IMAGE] genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DHX16 [IMAGE] genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DHX16 miRNA Products: miRTarBase miRNAs that target DHX16: hsa-mir-92a-3p (MIRT049188), hsa-mir-107 (MIRT048294), hsa-let-7b-5p (MIRT032275) [IMAGE] Block miRNA regulation of human, mouse, rat DHX16 using miScript Target Protectors [IMAGE] 2 qRT-PCR Assays for microRNAs that regulate DHX16: hsa-miR-188-3p hsa-miR-590-3p [IMAGE] SwitchGear 3'UTR luciferase reporter plasmid: DHX16 3' UTR sequence Inhib. RNA Products: [IMAGE] OriGene RNAi products in human, mouse, rat for DHX16 [IMAGE] Predesigned siRNA for gene silencing in human, mouse, rat DHX16 Gene Editing Products: [IMAGE] DNA2.0 Custom Protein Engineering Service for DHX16 Clone Products: [IMAGE] OriGene clones in human, mouse for DHX16 (see all 12) OriGene ORF clones in mouse, rat for DHX16 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling [IMAGE] GenScript: all cDNA clones in your preferred vector (see all 2): DHX16 (NM_001164239) [IMAGE] Sino Biological Human cDNA Clone for DHX16 [IMAGE] DNA2.0 Custom Codon Optimized Gene Synthesis Service for DHX16 [IMAGE] Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DHX16 Cell Line Products: [IMAGE] GenScript Custom overexpressing Cell Line Services for DHX16 [IMAGE] Browse ESI BIO Cell Lines and PureStem Progenitors for DHX16 [IMAGE] In Situ Assay Products: [IMAGE] Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DHX16
  • Similarity:
    Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily
                          
    Contains 1 helicase ATP-binding domain
                          
    Contains 1 helicase C-terminal domain [IMAGE]
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR001650Helicase_CHelicase, C-terminalDomain
    IPR002464DNA/RNA_helicase_DEAH_CSATP-dependent helicase, DEAH-boxFamily
    IPR007502Helicase-assoc_domHelicase-associated regionDomain
    IPR011545DNA/RNA_helicase_DEAD/DEAH_NDEAD/DEAH box helicase, N-terminalDomain
    IPR011709DUF1605Protein of unknown function DUF1605Domain
    BlocksIPB002464ATP-dependent helicaseATP-dependent helicase, DEAH-box
    IPB007502Helicase-associated regionHelicase-associated region

    Gene Ontology    
    Type Term Evidence Source Pub
    Molecular Function RNA helicase activity TAS GOA 9547260

    DHX16 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene