Gene content    
DNAJB4 ( by HUGO)
DnaJ (Hsp40) Homolog, Subfamily B, Member 4
Tumor suppressor gene
DnaJ (Hsp40) Homolog
Subfamily B
Member 4
Heat Shock 40 KDa Protein 1 Homolog
Heat Shock Protein 40 Homolog
Human Liver DnaJ-Like Protein
DNAJW
HLJ1
HSP40 Homolog
DjB4
DnaJ Homolog Subfamily B Member 4
DnaJ-Like Heat Shock Protein 40
NCBI: 1p31.1    Ensembl: 1p31.1
DNJB4_HUMANSize: 337 amino acidsMass: 37807 Da

  • Subunit: Homodimer. The C-terminal section interacts with the C-terminal tail of OPRM1. Interacts also with SDIM1
  • Tissue specificity: Expressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver [IMAGE] Pathway & Disease-focused RT2 Profiler PCR Arrays including DNAJB4: Cellular Stress Responses in human mouse rat Heat Shock Proteins & Chaperones
  • Function:
    UniProtKB/Swiss-Prot Summary: DNJB4_HUMAN, Q9UDY4 Function: Probable chaperone
  • Similarity:
    Contains 1 J domain [IMAGE]
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR001623DnaJ_domainHeat shock protein DnaJ, N-terminalDomain
    IPR002939DnaJ_CChaperone DnaJ, C-terminalDomain
    IPR008971HSP40/DnaJ_pept-bdHSP40/DnaJ peptide-bindingDomain

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process response to heat TAS GOA 9546042
    response to unfolded protein TAS GOA 9546042

    DNAJB4 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene