Gene content
Symbol	ETS2 ( by HUGO)
Name	V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog...
Category	Oncogene
Alias	V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 2 V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (Avian) Human Erythroblastosis Virus Oncogene Homolog 2 ETS2IT1 Oncogene ETS-2 Protein C-Ets-2 V-Ets Avian Erythroblastosis Virus E2 Oncogene Homolog 2 V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2
Cytogenetic band	NCBI: 21q22.2    Ensembl: 21q22.2
Protein information	ETS2_HUMAN Size: 469 amino acids Mass: 53001 Da Function: UniProtKB/Swiss-Prot Summary: ETS2_HUMAN, P15036 Function: Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription Similarity: Belongs to the ETS family                        Contains 1 ETS DNA-binding domain                        Contains 1 PNT (pointed) domain [IMAGE]

Protein Domain/Family
Source	ID	Domain	Name	Type
InterPro	IPR000418	Ets_dom	Ets	Domain
	IPR003118	Pointed_dom	Sterile alpha motif/pointed	Domain
	IPR011991	WHTH_DNA-bd_dom	Winged helix repressor DNA-binding	Domain

Gene Ontology
Type	Term	Evidence	Source	Pub
Biological Process	negative regulation of transcription from RNA polymerase II promoter	IDA	GOA	12637547
	positive regulation of transcription, DNA-templated	IDA	GOA	11909962
	skeletal system development	TAS	GOA	8596630
Cellular Component	nucleus	IDA	GOA	16780588
Molecular Function	DNA binding	TAS	GOA	10918595
	protein binding	IPI	GOA	11909962
	RNA polymerase II core promoter proximal region sequence-specific DNA binding	IDA	GOA	12637547
	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	IDA	GOA	12637547
	sequence-specific DNA binding transcription factor activity	IDA	GOA	11909962

ETS2 cross reference
PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene