Gene content    
ETV3 ( by HUGO)
Ets Variant 3
Oncogene
Ets Variant 3
PE1
Ets Variant Gene 3
ETS Family Transcriptional Repressor
Mitogenic Ets Transcriptional Suppressor
METS
PE-1
ETS Domain Transcriptional Repressor PE1
Ets Variant Gene 3
bA110J1.4
ETS Translocation Variant 3
NCBI: 1q21-q23    Ensembl: 1q23.1
ETV3_HUMANSize: 512 amino acidsMass: 57001 Da

  • Function:
    UniProtKB/Swiss-Prot Summary: ETV3_HUMAN, P41162 Function: Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity
  • Similarity:
    Belongs to the ETS family
                          
    Contains 1 ETS DNA-binding domain [IMAGE]
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR000418Ets_domEtsDomain
    IPR011991WHTH_DNA-bd_domWinged helix repressor DNA-bindingDomain

    ETV3 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene