Gene content  |
| EXTL3 ( by HUGO) |
| Exostosin-Like Glycosyltransferase 3 |
| Tumor suppressor gene |
| Exostosin-Like Glycosyltransferase 3 Glucuronyl-Galactosyl-Proteoglycan 4-Alpha-N-Acetylglucosaminyltransferase EXTR1 Exostoses (Multiple)-Like 3 REG Receptor Hereditary Multiple Exostoses Gene Isolog Putative Tumor Suppressor Protein EXTL3 EXTL1L BOTV REGR RPR Exostosin Tumor-Like 3 Exostosin-Like 3 EXT-Related 1 EC 2.4.1.223 KIAA0519 EXT-Related Protein 1 Multiple Exostosis-Like Protein 3 |
| NCBI: 8p21 Ensembl: 8p21.1 |
|
Subunit: Interacts with REG3A Caution: It is uncertain whether Met-1, Met-6 or Met-20 is the initiator Sequence caution: Sequence=BAA25445.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Tissue specificity: Ubiquitous. Expressed in keratinocytes [IMAGE] Custom PCR Arrays for EXTL3 Primer Products: [IMAGE] OriGene qPCR primer pairs and template standards for EXTL3 OriGene qSTAR qPCR primer pairs in human, mouse for EXTL3 [IMAGE] Pre-validated RT2 qPCR Primer
Function: Probable glycosyltransferase (By similarity). Required for the function of REG3A in regulating keratinocyte proliferation and differentiation Probable glycosyltransferase (By similarity). Required for the function of REG3A in regulating keratinocyte proliferation and differentiation
Catalytic activity: UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan
Similarity: Belongs to the glycosyltransferase 47 family [IMAGE]
|
