Gene content    
FARSLB (approved by HUGO)
phenylalanine-tRNA synthetase-like, beta subunit
Other
EC 6.1.1.20
FARSB
FRSB
PheHB
PheRS
NCBI: 2q36.1    Ensembl: 2q36.1
SYFB_HUMANSize: 589 amino acidsMass: 66130 Da

  • Subcellular location: Cytoplasm (By similarity)
  • Subunit: Tetramer of two alpha and two beta chains (By similarity)
  • Catalytic activity:
    ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe)
  • Similarity:
    Belongs to the phenylalanyl-tRNA synthetase beta chain family. Type 2 subfamily.

    • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR004531PheT_archPhenylalanyl-tRNA synthetase, beta subunit archae/euk cytosolicFamily
    IPR005146B3_4B3/4Domain
    IPR005147B5tRNA synthetase, B5Domain
    BlocksIPB005147tRNA synthetase B5 domaintRNA synthetase B5 domain

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process ATP binding IEA GOA
    ligase activity IEA GOA
    phenylalanine-tRNA ligase activity TAS GOA PubMed
    Cellular Component nucleotide binding IEA GOA
    Molecular Function cytoplasm TAS GOA PubMed
    phenylalanyl-tRNA aminoacylation IEA GOA
    protein biosynthesis TAS GOA PubMed
    soluble fraction TAS GOA PubMed

    FARSLB cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene