Gene content
Symbol	FAT (approved by HUGO)
Name	FAT tumor suppressor homolog 1 (Drosophila)
Category	Tumor suppressor gene
Alias	CDHF7 FAT1 ME5 hFat1
Cytogenetic band	NCBI: 4q35    Ensembl: 4q35.2
Protein information	FATH_HUMAN Size: 4590 amino acids Mass: 506278 Da Subcellular location: Membrane; single-pass type I membrane protein (By similarity) Tissue specificity: Expressed in many epithelial and some endothelial and smooth muscle cells Function: Could function as a cell-adhesion protein Similarity: Contains 34 cadherin domains                        Contains 5 EGF-like domains                        Contains 1 laminin G-like domain.

Protein Domain/Family
Source	ID	Domain	Name	Type
InterPro	IPR000152	Asx_hydroxyl_S	Aspartic acid and asparagine hydroxylation site	PTM
	IPR000742	EGF_2	EGF-like, subtype 2	Domain
	IPR001791	Laminin_G	Laminin G	Domain
	IPR001881	EGF_Ca_bd	EGF-like calcium-binding	Domain
	IPR002126	Cadherin	Cadherin	Domain
	IPR006209	EGF_like	EGF-like	Domain
	IPR012680	Laminin_G_2	Laminin G, subdomain 2	Domain
Blocks	IPB000152	Aspartic acid and asparagine hydroxylation site	Aspartic acid and asparagine hydroxylation site
	IPB001791	Laminin G	Laminin G
	IPB001881	EGF-like calcium-binding	EGF-like calcium-binding
	IPB002126	Cadherin	Cadherin
	IPB003129	Thrombospondin	Thrombospondin, N-terminal

Gene Ontology
Type	Term	Evidence	Source	Pub
Biological Process	calcium ion binding	IEA	GOA
	membrane	IEA	GOA
	morphogenesis	TAS	GOA	PubMed
	protein binding	IEA	GOA
Molecular Function	cell adhesion	TAS	GOA	PubMed
	cell-cell signaling	TAS	GOA	PubMed
	homophilic cell adhesion	IEA	GOA
	integral to plasma membrane	TAS	GOA	PubMed

FAT cross reference
PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene