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Subunit: Directly interacts with SKP1 and CUL1 (By similarity) Sequence caution: Sequence=CAD28506.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Function: UniProtKB/Swiss-Prot Summary: FXL13_HUMAN, Q8NEE6 Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By similarity) Gene Ontology (GO): 1 molecular function term: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0005515 protein binding -- -- [IMAGE] Find genes that share ontologies with FBXL13 About GenesLikeMe Phenotypes: 3 GenomeRNAi human phenotypes for FBXL13: Increased G1 DNA content Increased cell death HMECs cel Increased gamma-H2AX phosphory 1 MGI phenotypic allele [IMAGE] for Fbxl13 (no phenotypes) [IMAGE] Find genes that share phenotypes with FBXL13 About GenesLikeMe Animal Models: [IMAGE] inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FBXL13 [IMAGE] inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FBXL13 [IMAGE] genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FBXL13 [IMAGE] genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FBXL13 miRNA Products: [IMAGE] Block miRNA regulation of human, mouse, rat FBXL13 using miScript Target Protectors [IMAGE] Search for qRT-PCR Assays for microRNAs that regulate FBXL13 [IMAGE] SwitchGear 3'UTR luciferase reporter plasmid: FBXL13 3' UTR sequence Inhib. RNA Products: [IMAGE] OriGene RNAi products in human, mouse, rat for FBXL13 [IMAGE] Predesigned siRNA for gene silencing in human, mouse, rat FBXL13 Gene Editing Products: [IMAGE] DNA2.0 Custom Protein Engineering Service for FBXL13 Clone Products: [IMAGE] OriGene clones in human, mouse for FBXL13 (see all 11) OriGene ORF clones in mouse, rat for FBXL13 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling [IMAGE] GenScript: all cDNA clones in your preferred vector (see all 2): FBXL13 (NM_001111038) [IMAGE] Browse Sino Biological Human cDNA Clones [IMAGE] DNA2.0 Custom Codon Optimized Gene Synthesis Service for FBXL13 [IMAGE] Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FBXL13 Cell Line Products: [IMAGE] GenScript Custom overexpressing Cell Line Services for FBXL13 [IMAGE] Browse ESI BIO Cell Lines and PureStem Progenitors for FBXL13 [IMAGE] In Situ Assay Products: [IMAGE] Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXL13
Similarity: Contains 1 F-box domain Contains 17 LRR (leucine-rich) repeats [IMAGE]
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