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Subunit: Homodimer. Part of a ternary complex that contains CEP350, FGFR1OP and MAPRE1. Interacts directly with CEP350 and MAPRE1 1 PDB 3D structure from [IMAGE] and Proteopedia [IMAGE] for FGFR1OP: 2D68 (3D) [IMAGE]
Tissue specificity: Ubiquitous. Highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas [IMAGE] Custom PCR Arrays for FGFR1OP Primer Products: [IMAGE] OriGene qPCR primer pairs and template standards for FGFR1OP OriGe
Function: UniProtKB/Swiss-Prot Summary: FR1OP_HUMAN, O95684 Function: Required for anchoring microtubules to the centrosomes Gene Ontology (GO): 5 molecular function terms: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0004713 protein tyrosine kinase activity TAS -- GO:0005515 protein binding IPI 17888034 GO:0019901 protein kinase binding IPI 17888034 GO:0030292 protein tyrosine kinase inhibitor activity IDA 17888034 GO:0042803 protein homodimerization activity IDA 16690081 [IMAGE] Find genes that share ontologies with FGFR1OP About GenesLikeMe Phenotypes: 1 MGI phenotypic allele [IMAGE] for Fgfr1op (no phenotypes) [IMAGE] Find genes that share phenotypes with FGFR1OP About GenesLikeMe Animal Models: [IMAGE] inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FGFR1OP [IMAGE] inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FGFR1OP [IMAGE] genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FGFR1OP [IMAGE] genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FGFR1OP miRNA Products: miRTarBase miRNAs that target FGFR1OP: hsa-mir-192-5p (MIRT026178) [IMAGE] Block miRNA regulation of human, mouse, rat FGFR1OP using miScript Target Protectors [IMAGE] 7 qRT-PCR Assays for microRNAs that regulate FGFR1OP: hsa-miR-495 hsa-miR-1184 hsa-miR-124 hsa-miR-1252 hsa-miR-506 hsa-miR-219-5p hsa-miR-1205 [IMAGE] SwitchGear 3'UTR luciferase reporter plasmid: FGFR1OP 3' UTR sequence Inhib. RNA Products: [IMAGE] OriGene RNAi products in human, mouse, rat for FGFR1OP [IMAGE] Predesigned siRNA for gene silencing in human, mouse, rat FGFR1OP Gene Editing Products: [IMAGE] DNA2.0 Custom Protein Engineering Service for FGFR1OP Clone Products: [IMAGE] OriGene clones in human, mouse for FGFR1OP (see all 14) OriGene ORF clones in mouse, rat for FGFR1OP OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling [IMAGE] GenScript: all cDNA clones in your preferred vector (see all 2): FGFR1OP (NM_007045) [IMAGE] Sino Biological Human cDNA Clone for FGFR1OP [IMAGE] DNA2.0 Custom Codon Optimized Gene Synthesis Service for FGFR1OP [IMAGE] Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FGFR1OP Cell Line Products: [IMAGE] GenScript Custom overexpressing Cell Line Services for FGFR1OP [IMAGE] Browse ESI BIO Cell Lines and PureStem Progenitors for FGFR1OP [IMAGE] In Situ Assay Products: [IMAGE] Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FGFR1OP
Similarity: Belongs to the FGFR1OP family Contains 1 LisH domain [IMAGE]
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