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Subunit: Interacts with IKZF3 1 PDB 3D structure from [IMAGE] and Proteopedia [IMAGE] for FOXP3: 3QRF (3D) [IMAGE]
Function: UniProtKB/Swiss-Prot Summary: FOXP3_HUMAN, Q9BZS1 Function: Probable transcription factor. Plays a critical role in the control of immune response Gene Ontology (GO): Selected molecular function terms (see all 14): About this table GO ID Qualified GO term Evidence PubMed IDs GO:0003682 chromatin binding IBA -- GO:0003700 sequence-specific DNA binding transcription factor activity NAS 11138001 GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity IEA -- GO:0003714 transcription corepressor activity IBA -- GO:0005515 protein binding IPI 16652169 [IMAGE] Find genes that share ontologies with FOXP3 About GenesLikeMe Phenotypes: 1 GenomeRNAi human phenotype for FOXP3: Decreased number of cells in m Selected MGI mutant phenotypes (inferred from 26 alleles[IMAGE]) (MGI details for Foxp3) (see all 21): behavior/neurological cardiovascular system cellular craniofacial digestive/alimentary endocrine/exocrine gland growth/size/body hearing/vestibular/ear hematopoietic system homeostasis/metabolism immune system integument limbs/digits/tail liver/biliary system mortality/aging [IMAGE] Find genes that share phenotypes with FOXP3 About GenesLikeMe Animal Models: MGI mouse knock-outs for FOXP3: Foxp3tm1Tch Foxp3tm1.1Ayr [IMAGE] inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FOXP3 [IMAGE] inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FOXP3 [IMAGE] genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FOXP3 [IMAGE] genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FOXP3 miRNA Products: miRTarBase miRNAs that target FOXP3: hsa-mir-31-5p (MIRT001180) [IMAGE] Block miRNA regulation of human, mouse, rat FOXP3 using miScript Target Protectors [IMAGE] 4 qRT-PCR Assays for microRNAs that regulate FOXP3: hsa-miR-3164 hsa-miR-3611 hsa-miR-1827 hsa-miR-490-5p [IMAGE] SwitchGear 3'UTR luciferase reporter plasmid: FOXP3 3' UTR sequence Inhib. RNA Products: [IMAGE] OriGene RNAi products in human, mouse, rat for FOXP3 [IMAGE] Predesigned siRNA for gene silencing in human, mouse, rat FOXP3 Gene Editing Products: [IMAGE] DNA2.0 Custom Protein Engineering Service for FOXP3 Clone Products: [IMAGE] OriGene clones in human, mouse for FOXP3 (see all 10) OriGene ORF clones in mouse, rat for FOXP3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling [IMAGE] GenScript: all cDNA clones in your preferred vector (see all 2): FOXP3 (NM_014009) [IMAGE] Sino Biological Human cDNA Clone for FOXP3 [IMAGE] DNA2.0 Custom Codon Optimized Gene Synthesis Service for FOXP3 [IMAGE] Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FOXP3 [IMAGE] Addgene plasmids for FOXP3 [IMAGE] Cell Line Products: [IMAGE] GenScript Custom overexpressing Cell Line Services for FOXP3 [IMAGE] Browse ESI BIO Cell Lines and PureStem Progenitors for FOXP3 [IMAGE] In Situ Assay Products: [IMAGE] Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FOXP3 Flow Cytometry Products: [IMAGE] eBioscience FlowRNA Probe Sets (VA1-13420 VA6-12565) for FOXP3 [IMAGE]
Similarity: Contains 1 C2H2-type zinc finger Contains 1 fork-head DNA-binding domain [IMAGE]
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