Gene content    
FRAT2 ( by HUGO)
Frequently Rearranged In Advanced T-Cell Lymphomas
Oncogene
Frequently Rearranged In Advanced T-Cell Lymphomas 2
GSK-3 Binding Protein FRAT2
FRAT-2
GSK-3-Binding Protein FRAT2
NCBI: 10q24.1    Ensembl: 10q24.1
FRAT2_HUMANSize: 233 amino acidsMass: 24051 Da

  • Subunit: Binds GSK-3 and prevents GSK-3-dependent phosphorylation
  • Function:
    UniProtKB/Swiss-Prot Summary: FRAT2_HUMAN, O75474 Function: Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3 Gene Ontology (GO): 1 molecular function term: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0003674 molecular_function ND -- [IMAGE] Find genes that share ontologies with FRAT2 About GenesLikeMe Phenotypes:
  • Similarity:
    Belongs to the GSK-3-binding protein family [IMAGE]

    • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR008014GSK3-bdGlycogen synthase kinase-3 binding proteinFamily
    BlocksIPB008014Glycogen synthase kinase-3 binding proteinGlycogen synthase kinase-3 binding protein

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process cell proliferation NAS GOA 9635432
    multicellular organismal development NAS GOA 9635432

    FRAT2 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene