Gene content    
GLS (-- by HUGO)
glutaminase GLS: Approved
--
EC 3.5.1.2
glutaminase
GAC
GLS1
GAM
KIAA0838
KGA
K-glutaminase
glutaminase
L-glutamine
amidohydrolase
glutaminase
kidney
mitochondrial
phosphate-activated
NCBI: 2q32-q34    Ensembl: 2q32.2
GLSK_HUMANSize: 669 amino acidsMass: 73461 Da

  • Subcellular location: Mitochondrion (Probable)
  • Tissue specificity: KGA is expressed predominantly in brain and kidney but not in liver, isoform 3 is expressed principally in cardiac muscle and pancreas but not in liver or brain, and isoform 2 is expressed solely in cardiac and skeletal muscle
  • Similarity:
    Belongs to the glutaminase family
                          
    Contains 1 ANK repeat
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR002110Ankyrin_rptAnkyrinRepeat
    IPR012338Beta-lactam/transpept-likePenicillin-binding protein, transpeptidase foldDomain
    BlocksIPB002110Ankyrin repeat signatureAnkyrin repeat signature
    IPB007043GlutaminaseGlutaminase

    GLS cross reference    
    PubMed Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene