Gene content    
GPRC5A ( by HUGO)
G Protein-Coupled Receptor, Class C, Group 5, Member A
Tumor suppressor gene
G Protein-Coupled Receptor
Class C
Group 5
Member A
RAI3
GPCR5A
RAIG1
G Protein-Coupled Receptor
Family C
Group 5
Member A
Retinoic Acid Induced 3
Orphan G-Protein-Coupling Receptor PEIG-1
Retinoic Acid-Induced Gene 1 Protein
RAIG-1
G-Protein Coupled Receptor Family C Group 5 Member A
Retinoic Acid Responsive
Retinoic Acid-Induced Protein 3
NCBI: 12p13-p12.3    Ensembl: 12p13.1
RAI3_HUMANSize: 357 amino acidsMass: 40251 Da

  • Tissue specificity: Expressed at high level in fetal and adult lung tissues. Constitutively expressed in fetal kidney and adult placenta, kidney, prostate, testis, ovary, small intestine, colon, stomach, and spinal chord at low to moderate levels. Not detectable in fetal hea
  • Function:
    UniProtKB/Swiss-Prot Summary: RAI3_HUMAN, Q8NFJ5 Function: Unknown. This G-protein coupled receptor could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. The comparable expression level in fetal lung and kidney with adult tissues suggests a possible role in embryonic development and maturation of these organs. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways
  • Similarity:
    Belongs to the G-protein coupled receptor 3 family [IMAGE]
  • Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process signal transduction TAS GOA 9857033
    Cellular Component extracellular vesicular exosome IDA GOA 19056867
    integral component of plasma membrane TAS GOA 9857033

    GPRC5A cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene