Gene content
Symbol	GSTM1 ( by HUGO)
Name	Glutathione S-Transferase Mu 1
Category	Tumor suppressor gene & --
Alias	Glutathione S-Transferase Mu 1 GST1 Glutathione S-Transferase M1 GSTM1-1 GSTM1a-1a GSTM1b-1b GTH4 GST Class-Mu 1 GST HB Subunit 4 EC 2.5.1.18 GTM1 H-B MU MU-1 Glutathione S-Alkyltransferase Glutathione S-Aralkyltransferase Glutathione S-Aryltransferase HB Subunit 4 S-(Hydroxyalkyl)Glutathione Lyase
Cytogenetic band	NCBI: 1p13.3    Ensembl: 1p13.3
Protein information	GSTM1_HUMAN Size: 218 amino acids Mass: 25712 Da Subunit: Homodimer 5 PDB 3D structures from [IMAGE] and Proteopedia [IMAGE] for GSTM1: 1GTU (3D) [IMAGE] 1XW6 (3D) [IMAGE] 1XWK (3D) [IMAGE] 1YJ6 (3D) [IMAGE] 2F3M (3D) [IMAGE] Tissue specificity: Liver (at protein level) [IMAGE] Custom PCR Arrays for GSTM1 Primer Products: [IMAGE] OriGene qPCR primer pairs and template standards for GSTM1 OriGene qSTAR qPCR primer pairs in human, mouse for GSTM1 [IMAGE] Pre-validated RT2 qPCR Primer Assay in human Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles                        Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles Catalytic activity: RX + glutathione = HX + R-S-glutathione Similarity: Belongs to the GST superfamily. Mu family                        Contains 1 GST C-terminal domain                        Contains 1 GST N-terminal domain [IMAGE]

Protein Domain/Family
Source	ID	Domain	Name	Type
InterPro	IPR003081	GST_mu	Glutathione S-transferase, Mu class	Family
	IPR004045	Glutathione_S-Trfase_N	Glutathione S-transferase, N-terminal	Domain
	IPR004046	GST_C	Glutathione S-transferase, C-terminal	Domain
	IPR010987	Glutathione-S-Trfase_C-like	Glutathione S-transferase, C-terminal-like	Domain
	IPR012336	Thioredoxin-like_fold	Thioredoxin-like fold	Domain
Blocks	IPB003081	Mu-class glutathione S-transferase signature	Mu-class glutathione S-transferase signature

Gene Ontology
Type	Term	Evidence	Source	Pub
Biological Process	glutathione transferase activity	IEA	GOA
	glutathione transferase activity	TAS	GOA	PubMed
	metabolism	IEA	GOA
	transferase activity	IEA	GOA
Molecular Function	cytoplasm	NR	GOA

GSTM1 cross reference
PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene