TAG for GTF2F2

Gene content

Symbol

GTF2F2 (-- by HUGO)

Name

general transcription factor IIF, polypeptide 2, 30kDa (Previous names: general transcription factor

Category

Alias

EC 3.6.4.12
general
transcription
factor
polypeptide
30kDa
TFIIF-beta
RAP30
ATP-dependent
helicase
GTF2F2
BTF4
general
transcription
factor
polypeptide
(74kD
subunit)
TFIIF
TF2F2
General
transcription
factor
IIF
30
kDa
subunit
general
transcription
factor
IIF
subunit
Transcription
initiation
factor
IIF
subunit
beta
Transcription
initiation
factor
RAP30
EC

Cytogenetic band

NCBI: 13q14 Ensembl: 13q14.12

Protein information

T2FB_HUMAN

Size: 249 amino acids

Mass: 28380 Da

Subcellular location: Nucleus PDB 3D structures from [IMAGE] and Proteopedia [IMAGE] : 1BBY (3D) [IMAGE] 1F3U (3D) [IMAGE] 2BBY (3D) [IMAGE] Secondary accessions: A6NNS5 Q5W0H3 Explore the universe of human proteins at neXtProt for GTF2F2: NX_P13984 Post-translational modifica

Subunit: Heterodimer of an alpha and a beta subunit. Interacts with HTATSF1 and GPBP1 (By similarity). Interacts with URI1

Similarity:

Belongs to the TFIIF beta subunit family

Protein Domain/Family
Source	ID	Domain	Name	Type
InterPro	IPR003196	TFIIF_beta	Transcription initiation factor IIF, beta subunit	Family
	IPR011039	TFIIF_interaction	Transcription Factor IIF, Rap30/Rap74, interaction	Domain
	IPR011991	WHTH_trsnscrt_rep_DNA-bd	Winged helix repressor DNA-binding	Domain
Blocks	IPB003196	Transcription initiation factor IIF	Transcription initiation factor IIF, beta subunit

GTF2F2 cross reference