Gene content    
IL24 ( by HUGO)
Interleukin
Tumor suppressor gene
Interleukin 24
ST16
MDA7
IL-4-Induced Secreted Protein
Suppression Of Tumorigenicity 16 (Melanoma Differentiation)
Melanoma Differentiation-Associated Gene 7 Protein
Melanoma Differentiation Association Protein 7
C49A
FISP
IL10B
MOB5
interleukin-24
Melanocyte-Associated Mda-7
IL-24
MDA-7
Suppression Of Tumorigenicity 16 Protein
NCBI: 1q32    Ensembl: 1q32.1
IL24_HUMANSize: 206 amino acidsMass: 23825 Da

  • Tissue specificity: Up-regulated in melanoma cells induced to terminally differentiate [IMAGE] Pathway & Disease-focused RT2 Profiler PCR Arrays including IL24: Th1/Th2 Response in human mouse rat Cytokines & Chemokines in human mouse rat Common Cytokines in human mouse rat
  • Function:
    UniProtKB/Swiss-Prot Summary: IL24_HUMAN, Q13007 Function: Has antiproliferative properties on melanoma cells and may contribute to terminal cell differentiation Gene Ontology (GO): 2 molecular function terms: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0005125 cytokine activity IEA -- GO:0005515 protein binding -- -- [IMAGE] Find genes that share ontologies with IL24 About GenesLikeMe Phenotypes: 1 GenomeRNAi human phenotype for IL24: Increased gamma-H2AX phosphory
  • Similarity:
    Belongs to the IL-10 family [IMAGE]
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR0090794_helix_cytokine-like_coreFour-helical cytokineFamily
    IPR0123514_helix_cytokine_coreCytokine, four-helical bundleDomain
    BlocksIPB000098Interleukin-10Interleukin-10

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process apoptotic process TAS GOA 9826712

    IL24 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene