Gene content    
JUND ( by HUGO)
Jun D Proto-Oncogene
Oncogene
Jun D Proto-Oncogene
Activator Protein 1
JunD-FL Isoform
Transcription Factor Jun-D
AP-1
NCBI: 19p13.2    Ensembl: 19p13.11
JUND_HUMANSize: 347 amino acidsMass: 35174 Da

  • Subunit: Binds DNA as a dimer (By similarity). Interacts with MEN1; this interaction represses transcriptional activation Sequence caution: Sequence=CAA40010.1; Type=Frameshift; Positions=Several; 1 PDB 3D structure from [IMAGE] and Proteopedia [IMAGE] for JUND: 3U86 (3D) [IMAGE]
  • Function:
    UniProtKB/Swiss-Prot Summary: JUND_HUMAN, P17535 Function: Transcription factor binding AP-1 sites
  • Similarity:
    Belongs to the bZIP family. Jun subfamily
                          
    Contains 1 bZIP (basic-leucine zipper) domain [IMAGE]

    • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR002112Leuzip_JunTranscription factor JunFamily
    IPR004827bZIPBasic-leucine zipper (bZIP) transcription factorDomain
    IPR005643JNKJun-like transcription factorDomain
    IPR008917TF_DNA-bdEukaryotic transcription factor, DNA-bindingDomain
    BlocksIPB002112Jun transcription factor signatureJun transcription factor signature
    IPB005643Jun-like transcription factorJun-like transcription factor

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process regulation of transcription from RNA polymerase II promoter TAS GOA 1903194
    Cellular Component chromatin TAS GOA 1903194
    Molecular Function protein binding IPI GOA 17577209
    transcription regulatory region DNA binding IDA GOA 1903194

    JUND cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene