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Subunit: Monomer Developmental stage: Up-regulated during dendritic cell maturation 1 PDB 3D structure from [IMAGE] and Proteopedia [IMAGE] for LAMP3: 4AKM (3D) [IMAGE]
Tissue specificity: Detected in tonsil interdigitating dendritic cells, in spleen, lymph node, Peyer's patches in the small instestine, in thymus medulla and in B cells (at protein level). Expressed in lymphoid organs and dendritic cells. Expressed in lung. Up-regulated in c
Function: UniProtKB/Swiss-Prot Summary: LAMP3_HUMAN, Q9UQV4 Function: May play a role in dendritic cell function and in adaptive immunity Phenotypes: 1 GenomeRNAi human phenotype for LAMP3: Increased gamma-H2AX phosphory Animal Models: [IMAGE] inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for LAMP3 [IMAGE] inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for LAMP3 [IMAGE] genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for LAMP3 [IMAGE] genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for LAMP3 miRNA Products: miRTarBase miRNAs that target LAMP3: hsa-mir-26b-5p (MIRT029868) [IMAGE] Block miRNA regulation of human, mouse, rat LAMP3 using miScript Target Protectors [IMAGE] 4 qRT-PCR Assays for microRNAs that regulate LAMP3: hsa-miR-382 hsa-miR-3163 hsa-miR-149 hsa-miR-516b [IMAGE] SwitchGear 3'UTR luciferase reporter plasmid: LAMP3 3' UTR sequence Inhib. RNA Products: [IMAGE] OriGene RNAi products in human, mouse, rat for LAMP3 [IMAGE] Predesigned siRNA for gene silencing in human, mouse, rat LAMP3 Gene Editing Products: [IMAGE] DNA2.0 Custom Protein Engineering Service for LAMP3 Clone Products: [IMAGE] OriGene clones in human, mouse for LAMP3 (see all 6) OriGene ORF clones in mouse, rat for LAMP3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling [IMAGE] GenScript: all cDNA clones in your preferred vector: LAMP3 (NM_014398) [IMAGE] Sino Biological Human cDNA Clone for LAMP3 [IMAGE] DNA2.0 Custom Codon Optimized Gene Synthesis Service for LAMP3 [IMAGE] Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LAMP3 Cell Line Products: [IMAGE] GenScript Custom overexpressing Cell Line Services for LAMP3 [IMAGE] Browse ESI BIO Cell Lines and PureStem Progenitors for LAMP3 [IMAGE] In Situ Assay Products: [IMAGE] Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LAMP3 Flow Cytometry Products: [IMAGE] eBioscience FlowRNA Probe Sets (VA1-10269) for LAMP3 [IMAGE]
Similarity: Belongs to the LAMP family [IMAGE]
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