Gene content
Symbol	LHX1 ( by HUGO)
Name	LIM Homeobox 1
Category	Other
Alias	LIM Homeobox 1 LIM1 Homeobox Protein Lim-1 LIM-1 LIM Homeobox Protein 1 LIM/Homeobox Protein Lhx1 hLim-1
Cytogenetic band	NCBI: 17q12    Ensembl: 17q12
Protein information	LHX1_HUMAN Size: 406 amino acids Mass: 44808 Da Subunit: Interacts with LDB1 via the tandem LIM domains (By similarity) Tissue specificity: Expressed in the brain, thymus, and tonsils. Expressed in samples from patients with chronic myeloid leukemia (CML) and in 58% of acute myeloid leukemia (AML) cell lines [IMAGE] Pathway & Disease-focused RT2 Profiler PCR Array including LHX1: Homeobox (HO Function: UniProtKB/Swiss-Prot Summary: LHX1_HUMAN, P48742 Function: Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis Similarity: Contains 1 homeobox DNA-binding domain                        Contains 2 LIM zinc-binding domains [IMAGE]

Protein Domain/Family
Source	ID	Domain	Name	Type
InterPro	IPR001356	Homeobox_dom	Homeobox	Domain
	IPR001781	Znf_LIM	LIM, zinc-binding	Domain
	IPR009057	Homeodomain-like	Homeodomain-like	Domain
Blocks	IPB000047	Lambda and other repressor helix-turn-helix signature	Lambda and other repressor helix-turn-helix signature

Gene Ontology
Type	Term	Evidence	Source	Pub
Biological Process	nervous system development	TAS	GOA	9212161
	organ morphogenesis	TAS	GOA	7700351

LHX1 cross reference
PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene