Gene content |
| LIN28A (-- by HUGO) |
| lin-28 homolog A (C. elegans) (Previous name: lin-28 homolog (C. elegans) ) LIN28A: Approved |
| -- |
| lin-28homolog(C.elegans)lin-28homolog(C.elegans)LIN28lin-28ACSDD1proteinlin-28homologZCCHC1RNA-bindingproteinLIN-28LIN-28zincCCHCdomaincontainingZincfingerCCHCdomain-containingproteinLin-28A |
| NCBI: 1p36.11 Ensembl: 1p36.11 |
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Subcellular location: Cytoplasm. Nucleus, nucleolus. Note=Nucleolar localization observed in 10-15% of the nuclei in differentiated myotubes (By similarity). Shuttles between the cytoplasm and the nucleus. Localizes to cytoplasmic processing bodies and stress granules Developm
Subunit: During skeletal muscle differentiation, associated with translation initiation complexes in the polysomal compartment. Directly interacts with EIF3S2. Interaction with NCL is RNA-dependent (By similarity). Interacts with ZCCHC11/TUT4
Tissue specificity: Expressed in embryonic stem cells (ES cells), placenta and testis
Similarity: Belongs to the lin-28 family Contains 2 CCHC-type zinc fingers Contains 1 CSD (cold-shock) domain
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