Gene content    
LIN28A (-- by HUGO)
lin-28 homolog A (C. elegans) (Previous name: lin-28 homolog (C. elegans) ) LIN28A: Approved
--
lin-28
homolog
(C.
elegans)
lin-28
homolog
(C.
elegans)
LIN28
lin-28A
CSDD1
protein
lin-28
homolog
ZCCHC1
RNA-binding
protein
LIN-28
LIN-28
zinc
CCHC
domain
containing
Zinc
finger
CCHC
domain-containing
protein
Lin-28A
NCBI: 1p36.11    Ensembl: 1p36.11
LN28A_HUMANSize: 209 amino acidsMass: 22743 Da

  • Subcellular location: Cytoplasm. Nucleus, nucleolus. Note=Nucleolar localization observed in 10-15% of the nuclei in differentiated myotubes (By similarity). Shuttles between the cytoplasm and the nucleus. Localizes to cytoplasmic processing bodies and stress granules Developm
  • Subunit: During skeletal muscle differentiation, associated with translation initiation complexes in the polysomal compartment. Directly interacts with EIF3S2. Interaction with NCL is RNA-dependent (By similarity). Interacts with ZCCHC11/TUT4
  • Tissue specificity: Expressed in embryonic stem cells (ES cells), placenta and testis
  • Similarity:
    Belongs to the lin-28 family
                          
    Contains 2 CCHC-type zinc fingers
                          
    Contains 1 CSD (cold-shock) domain
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR001878Znf_CCHCZinc finger, CCHC-typeDomain
    IPR011129Cold_shock_protCold shock proteinDomain
    IPR012340NA-bd_OB-foldNucleic acid-binding, OB-fold, subgroupDomain
    BlocksIPB001878C2HC-type zinc-finger signatureC2HC-type zinc-finger signature

    LIN28A cross reference    
    PubMed Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene