Gene content    
LRRC17 ( by HUGO)
Leucine Rich Repeat Containing 17
Other
Leucine Rich Repeat Containing 17
P37NB
37 KDa Leucine-Rich Repeat (LRR) Protein
Leucine-Rich Repeat-Containing Protein 17
p37NB
NCBI: 7q22.1    Ensembl: 7q22.1
LRC17_HUMANSize: 441 amino acidsMass: 51800 Da

  • Tissue specificity: Expressed in osteoblast cell lines. Well expressed in ovary, heart, pancreas, skeletal muscle, lung, and fetal kidney and lung and only at the basal levels in the other tissues examined including adult kidney. More expressed in S-type neuroblastoma cells
  • Function:
    UniProtKB/Swiss-Prot Summary: LRC17_HUMAN, Q8N6Y2 Function: Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity) Gene Ontology (GO): 1 molecular function term: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0005515 protein binding -- -- [IMAGE] Find genes that share ontologies with LRRC17 About GenesLikeMe Phenotypes:
  • Similarity:
    Contains 6 LRR (leucine-rich) repeats
                          
    Contains 2 LRRCT domains
                          
    Contains 1 LRRNT domain [IMAGE]
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR000483Cys-rich_flank_reg_CCysteine-rich flanking region, C-terminalDomain
    IPR001611Leu-rich_rptLeucine-rich repeatRepeat

    LRRC17 cross reference    
    PubMed Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene