Gene content    
LSAMP ( by HUGO)
Limbic System-Associated Membrane Protein
Tumor suppressor gene
Limbic System-Associated Membrane Protein
IgLON Family Member 3
LAMP
IGLON3
NCBI: 3q13.2-q21    Ensembl: 3q13.32
LSAMP_HUMANSize: 338 amino acidsMass: 37393 Da

  • Tissue specificity: Expressed on limbic neurons and fiber tracts as well as in single layers of the superior colliculus, spinal chord and cerebellum [IMAGE] Custom PCR Arrays for LSAMP Primer Products: [IMAGE] OriGene qSTAR qPCR primer pairs in human, mouse for LSAMP [IMAGE]
  • Function:
    UniProtKB/Swiss-Prot Summary: LSAMP_HUMAN, Q13449 Function: Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hyppocampal mossy fiber projection (By similarity)
  • Similarity:
    Belongs to the immunoglobulin superfamily. IgLON family
                          
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains [IMAGE]
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR003598Ig_sub2Immunoglobulin C2 typeDomain
    IPR003599Ig_subImmunoglobulin subtypeDomain
    IPR007110Ig-like_domImmunoglobulin-likeDomain
    IPR013098Ig_I-setImmunoglobulin I-setDomain
    BlocksIPB003598Immunoglobulin C-2 typeImmunoglobulin C-2 type

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process nervous system development TAS GOA 8666243

    LSAMP cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene