Gene content    
MAFG ( by HUGO)
V-Maf Avian Musculoaponeurotic Fibrosarcoma Oncogene Homolog...
Oncogene
V-Maf Avian Musculoaponeurotic Fibrosarcoma Oncogene Homolog G
Basic Leucine Zipper Transcription Factor MafG
Transcription Factor MafG
hMAF
V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog G
NCBI: 17q25.3    Ensembl: 17q25.3
MAFG_HUMANSize: 162 amino acidsMass: 17850 Da

  • Tissue specificity: Highly expressed in skeletal muscle. Also expressed in heart and brain [IMAGE] Custom PCR Arrays for MAFG Primer Products: [IMAGE] OriGene qPCR primer pairs and template standards for MAFG OriGene qSTAR qPCR primer pairs in human, mouse for MAFG [IMAGE] P
  • Function:
    UniProtKB/Swiss-Prot Summary: MAFG_HUMAN, O15525 Function: Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. Activates globin gene expression when associated with NF-E2. May be involved in signal transduction of extracellular H(+) (By similarity)
  • Similarity:
    Belongs to the bZIP family. Maf subfamily
                          
    Contains 1 bZIP (basic-leucine zipper) domain [IMAGE]
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR004826bZIP_MafMaf transcription factorDomain
    IPR004827bZIPBasic-leucine zipper (bZIP) transcription factorDomain
    IPR008917TF_DNA-bdEukaryotic transcription factor, DNA-bindingDomain

    MAFG cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene