Gene content    
MMP11 ( by HUGO)
Matrix Metallopeptidase 11 (Stromelysin 3)
Tumor suppressor gene
Matrix Metallopeptidase 11 (Stromelysin 3)
STMY3
MMP-11
SL-3
ST3
Matrix Metalloproteinase 11 (Stromelysin 3)
Stromelysin III
stromelysin-3
EC 3.4.24.-
Matrix Metalloproteinase-11
EC 3.4.24
EC 3.4.24.24
NCBI: 22q11.23    Ensembl: 22q11.23
MMP11_HUMANSize: 488 amino acidsMass: 54590 Da

  • Tissue specificity: Specifically expressed in stromal cells of breast carcinomas [IMAGE] Pathway & Disease-focused RT2 Profiler PCR Arrays including MMP11: Extracellular Matrix & Adhesion Molecules in human mouse rat Tumor Metastasis in human mouse rat Primer Products: [IMAG
  • Function:
    UniProtKB/Swiss-Prot Summary: MMP11_HUMAN, P24347 Function: May play an important role in the progression of epithelial malignancies
  • Similarity:
    Belongs to the peptidase M10A family
                          
    Contains 4 hemopexin repeats [IMAGE]

    • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR000585Hemopexin-like_domHemopexinDomain
    IPR001818Pept_M10_metallopeptidasePeptidase M10A and M12B, matrixin and adamalysinFamily
    IPR006026Peptidase_MetalloPeptidase, metallopeptidasesDomain
    BlocksIPB000585Hemopexin repeatHemopexin repeat
    IPB001818MatrixinMatrixin

    Gene Ontology    
    Type Term Evidence Source Pub
    Cellular Component extracellular matrix IDA GOA 18622425

    MMP11 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene