Gene content  |
| MPP3 ( by HUGO) |
| Membrane Protein, Palmitoylated 3 (MAGUK P55 Subfamily Member... |
| Tumor suppressor gene |
| Membrane Protein Palmitoylated 3 (MAGUK P55 Subfamily Member 3) DLG3 MAGUK P55 Subfamily Member 3 Membrane Protein Palmitoylated 3 Discs Large Homolog 3 discs Large (Drosophila) Homolog 3 Discs Large Homolog 3 Protein MPP3 |
| NCBI: 17q21.31 Ensembl: 17q21.31 |
|
Subunit: May interact with HTR2A (By similarity). Interacts (via PDZ domain) with CADM1 (via C-terminus). Interacts with HTR4 (By similarity) Sequence caution: Sequence=AAH47017.1; Type=Erroneous initiation;
Function: Genatlas biochemistry entry for MPP3: membrane protein,palmitoylated 3,66kDa,involved in coupling the cytoskeleton to the cell membrane Gene Ontology (GO): 3 molecular function terms: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0004385 guanylate kinase activity TAS 8824795 GO:0005515 protein binding -- -- GO:0030165 PDZ domain binding IEA -- [IMAGE] Find genes that share ontologies with MPP3 About GenesLikeMe Phenotypes: 3 GenomeRNAi human phenotypes for MPP3: Increased cell death HMECs cel Small cells Upregulation of Wnt/beta-caten
Similarity: Belongs to the MAGUK family Contains 1 guanylate kinase-like domain Contains 2 L27 domains Contains 1 PDZ (DHR) domain Contains 1 SH3 domain [IMAGE]
|
