Gene content    
MRAS ( by HUGO)
Muscle RAS Oncogene Homolog
Oncogene
Muscle RAS Oncogene Homolog
RRAS3
Ras-Related Protein R-Ras3
M-RAs
R-RAS3
Muscle And Microspikes RAS
Ras-Related Protein M-Ras
NCBI: 3q22.3    Ensembl: 3q22.3
RASM_HUMANSize: 208 amino acidsMass: 23846 Da

  • Subunit: Interacts with RGL3. Interacts (active GTP-bound form preferentially) with RGS14 (By similarity). Forms a multiprotein complex with SHOC2, Raf (RAF1) and protein phosphatase 1 (PPP1CA, PPP1CB and PPP1CC)
  • Tissue specificity: Expression highly restricted to the brain and heart [IMAGE] Custom PCR Arrays for MRAS Primer Products: [IMAGE] OriGene qPCR primer pairs and template standards for MRAS OriGene qSTAR qPCR primer pairs in human, mouse for MRAS [IMAGE] Pre-validated RT2 qP
  • Function:
    UniProtKB/Swiss-Prot Summary: RASM_HUMAN, O14807 Function: May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway
  • Similarity:
    Belongs to the small GTPase superfamily. Ras family [IMAGE]

    • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR001806Small_GTPaseRas GTPaseFamily
    IPR005225Small_GTP-bd_domSmall GTP-binding protein domainDomain
    BlocksIPB001806Transforming protein P21 RAS signatureTransforming protein P21 RAS signature
    IPB003577Ras small GTPaseRas small GTPase, Ras type

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process actin cytoskeleton organization TAS GOA 9395237
    multicellular organismal development TAS GOA 10446149
    muscle organ development TAS GOA 9395237
    Ras protein signal transduction TAS GOA 10446149
    Molecular Function GTP-dependent protein binding IPI GOA 10934204
    GTPase activity TAS GOA 10446149

    MRAS cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene