Gene content    
MTCP1 ( by HUGO)
Mature T-Cell Proliferation 1
Oncogene
Mature T-Cell Proliferation 1
Mature T-Cell Proliferation-1 Type B1
MTCP-1 Type B1
P13MTCP1
Mature T-Cell Proliferation 1 Isoform P13
p8MTCP1
Protein P13 MTCP-1
C6.1B
p13MTCP1
NCBI: Xq28    Ensembl: Xq28
MTCP1_HUMANSize: 107 amino acidsMass: 12600 Da

  • Subunit: Interacts with AKT1 and AKT2 (via PH domain). Does not interact with AKT3 Caution: MTCP1 and MTCP1NB are transcribed from the same promoter and could be considered the same gene
  • Tissue specificity: Not found at a significant level in any tissue [IMAGE] Pathway & Disease-focused RT2 Profiler PCR Array including MTCP1: PI3K-AKT Signaling Pathway in human mouse rat Primer Products: [IMAGE] OriGene qSTAR qPCR primer pairs in human, mouse for MTCP1 [IMAG
  • Function:
    UniProtKB/Swiss-Prot Summary: MTCP1_HUMAN, P56278 Function: Enhances the phosphorylation and activation of AKT1 and AKT2
  • Similarity:
    Belongs to the TCL1 family [IMAGE]

    • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR004832TCL1_MTCP1TCL1/MTCP1Family
    BlocksIPB004832TCL1/MTCP1 familyTCL1/MTCP1 family

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process cell proliferation TAS GOA 8361760

    Disorder & Mutation    
    Source Disease
    Genatlasprolymphocytic leukemia (T-PLL),with translocation t(X;14)(q28;q11) and breakpoint at MTCP1 locus
    SWISS-PROTNote=Detected in T-cell leukemia bearing a t(X;14) translocation. Plays a key role in T-cell prolymphocytic leukemia

    MTCP1 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene