Gene content
Symbol	MYBBP1A ( by HUGO)
Name	MYB Binding Protein (P160) 1a
Category	Tumor suppressor gene
Alias	MYB Binding Protein (P160) 1a P160 P53-Activated Protein-2 PAP2 Myb-Binding Protein 1A
Cytogenetic band	NCBI: 17p13.3    Ensembl: 17p13.2
Protein information	MBB1A_HUMAN Size: 1328 amino acids Mass: 148855 Da Subunit: Binds to and represses JUN and MYB via the leucine zipper regions present in these proteins. Also binds to and represses PPARGC1A: this interaction is abrogated when PPARGC1A is phosphorylated by MAPK1/ERK. Binds to and stimulates transcription by AHR. Binds to KPNA2. Component of the B-WICH complex, at least composed of SMARCA5/SNF2H, BAZ1B/WSTF, SF3B1, DEK, MYO1C, ERCC6, MYBBP1A and DDX21 (By similarity) Sequence caution: Sequence=CAB66530.1; Type=Erroneous initiation; Function: UniProtKB/Swiss-Prot Summary: MBB1A_HUMAN, Q9BQG0 Function: May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity)

Protein Domain/Family
Source	ID	Domain	Name	Type
InterPro	IPR007015	DNA_pol_V	DNA polymerase V	Family

Gene Ontology
Type	Term	Evidence	Source	Pub
Biological Process	osteoblast differentiation	IDA	GOA	16210410
	regulation of transcription, DNA-templated	TAS	GOA	10644447
Cellular Component	membrane	IDA	GOA	16210410
Molecular Function	protein binding	IPI	GOA	17255935
	transcription factor binding	TAS	GOA	10644447

MYBBP1A cross reference
PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene