Gene content
Symbol	NFKBIA (-- by HUGO)
Name	Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer... -----------------------------------------
Category	--
Alias	Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor, Alpha MAD-3 NFKBI ikB-alpha IKBA NF-Kappa-B Inhibitor Alpha Major Histocompatibility Complex Enhancer-Binding Protein MAD3 Nuclear Factor Of Kappa Light Chain Gene Enhancer In B-Cells I-kappa-B-alpha IkB-alpha IkappaBalpha MA
Cytogenetic band	NCBI: 14q13    Ensembl: 14q13.2
Protein information	IKBA_HUMAN Size: 317 amino acids Mass: 35609 Da Subcellular location: Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export (By similarity) 2 PDB 3D structures from [IMAGE] and Proteopedia [IMAGE] for NFKBIA: 1IKN (3D) [IMAGE] 1NFI Subunit: Interacts with RELA; the interaction requires the nuclear import signal. Interacts with NKIRAS1 and NKIRAS2. Part of a 70-90 kDa complex at least consisting of CHUK, IKBKB, NFKBIA, RELA, IKBKAP and MAP3K14. Interacts with HBV protein X. Interacts with RWDD3; the interaction enhances sumoylation. Interacts (when phosphorylated at the 2 serine residues in the destruction motif D-S-G-X(2,3,4)-S) with BTRC. Associates with the SCF(BTRC) complex, composed of SKP1, CUL1 and BTRC; the association is mediated via interaction with BTRC. Part of a SCF(BTRC)-like complex lacking CUL1, which is associated with RELA; RELA interacts directly with NFKBIA. Interacts with PRMT2. Interacts with PRKACA in platelets; this interaction is disrupted by thrombin and collagen. Interacts with HIF1AN

NFKBIA cross reference
PubMed Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene