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Subunit: Probable constituent of a neurofascin/NRCAM/ankyrin-G complex. Interacts with GLDN/gliomedin (By similarity) Sequence caution: Sequence=AAC50765.1; Type=Erroneous initiation; Sequence=BAA20801.2; Type=Erroneous initiation; 2 PDB 3D structures from [IMAGE] and Proteopedia [IMAGE] for NRCAM: 1UEN (3D) [IMAGE] 1UEY (3D) [IMAGE]
Tissue specificity: Detected in all the examined tissues. In the brain it was detected in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus [IMAGE] Pathway & Disease-focused RT2 Profiler PCR Arrays i
Function: UniProtKB/Swiss-Prot Summary: NRCAM_HUMAN, Q92823 Function: Cell adhesion, ankyrin-binding protein involved in neuron-neuron adhesion. May play a role in the molecular assembly of the nodes of Ranvier (By similarity)
Similarity: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family Contains 5 fibronectin type-III domains Contains 6 Ig-like C2-type (immunoglobulin-like) domains [IMAGE]
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