TAG for OAS1

Gene content

Symbol

OAS1 (-- by HUGO)

Name

2'-5'-oligoadenylate synthetase 1, 40/46kDa ------------------------------------------- (Previous na

Category

Alias

2'-5'-Oligoadenylate Synthetase 1, 40/46kDa
2',5'-Oligo A Synthetase 1
OIAS
2',5'-Oligoadenylate Synthetase 1, 40/46kDa
IFI-4
2'-5' Oligoadenylate Synthetase 1 P48 Isoform
OIASI
2'-5' Oligoadenylate Synthetase 1 P52 Isoform
(2-5')Oligo(A) Synthase 1
2'-5'-Oligoadenylate Synthase 1
2-5A Synthase 1
2'-5'-Oligoisoadenylate Synthetase 1
E18/E16
2-5A Synthetase 1
P46/P42 OAS
EC 2.7.7.-
2',5'-Oligoadenylate Synthetase 1 (40-46 KD)
EC 2.7.7
(2-5')Oligo(A) Synthetase

Cytogenetic band

NCBI: 12q24.2 Ensembl: 12q24.13

Protein information

OAS1_HUMAN

Size: 400 amino acids

Mass: 46029 Da

Subcellular location: Cytoplasm. Mitochondrion. Nucleus. Microsome. Endoplasmic reticulum. Secreted (By similarity). Note=Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions Caution: PubMed:1651324 sequence was

Subunit: Monomer (By similarity). Homotetramer

Similarity:

Belongs to the 2-5A synthase family

Protein Domain/Family
Source	ID	Domain	Name	Type
InterPro	IPR002934	Nucleotidyltransferase	DNA polymerase, beta-like region	Domain
	IPR006116	2-5-oligoadenylate_synth_N	2-5 oligoadenylate synthetase, ubiquitin-like region	Domain
	IPR006117	2-5-oligoadenylate_synth_CS	2-5-oligoadenylate synthetase	Domain
Blocks	IPB006117	2-5-oligoadenylate synthetase	2-5-oligoadenylate synthetase

OAS1 cross reference