Gene content    
PLAGL1 ( by HUGO)
Pleiomorphic Adenoma Gene-Like 1
Tumor suppressor gene
Pleiomorphic Adenoma Gene-Like 1
LOT1
ZAC
Lost On Transformation 1
Pleiomorphic Adenoma-Like Protein 1
Tumor Suppressor ZAC
LOT-1
ZAC1
PLAG-Like 1
Tumor Supressor ZAC
Zinc Finger Protein PLAGL1
NCBI: 6q24-q25    Ensembl: 6q24.2
PLAL1_HUMANSize: 463 amino acidsMass: 50819 Da

  • Subunit: Interacts with THRSP
  • Function:
    UniProtKB/Swiss-Prot Summary: PLAL1_HUMAN, Q9UM63 Function: Shows weak transcriptional activatory activity. Transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide
  • Similarity:
    Belongs to the krueppel C2H2-type zinc-finger protein family
                          
    Contains 7 C2H2-type zinc fingers [IMAGE]
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR007087Znf_C2H2Zinc finger, C2H2-typeDomain

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process cell cycle arrest TAS GOA 9184226
    positive regulation of transcription from RNA polymerase II promoter IDA GOA 15888726
    Molecular Function DNA binding IDA GOA 15888725
    RNA polymerase II regulatory region sequence-specific DNA binding IDA GOA 9671765

    PLAGL1 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene