Gene content    
PMS1 ( by HUGO)
PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae)
Other
PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae)
PMSL1
DNA Mismatch Repair Protein PMS1
HNPCC3
Postmeiotic Segregation Increased (S. Cerevisiae) 1
hPMS1
Human Homolog Of Yeast MutL
Mismatch Repair Gene PMSL1
PMS1 Protein Homolog 1
Rhabdomyosarcoma Antigen MU-RMS-40.10B
Rhabdomyosarcoma Antigen MU-RMS-40.10E
NCBI: 2q31.1    Ensembl: 2q32.2
PMS1_HUMANSize: 932 amino acidsMass: 105830 Da

  • Subunit: The MutL-beta complex is a heterodimer of PMS1 and MLH1 1 PDB 3D structure from [IMAGE] and Proteopedia [IMAGE] for PMS1: 2CS1 (3D) [IMAGE]
  • Function:
    UniProtKB/Swiss-Prot Summary: PMS1_HUMAN, P54277 Function: Probably involved in the repair of mismatches in DNA
  • Similarity:
    Belongs to the DNA mismatch repair MutL/HexB family
                          
    Contains 1 HMG box DNA-binding domain [IMAGE]

    • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR002099DNA_mismatch_repair_famDNA mismatch repair proteinFamily
    IPR003594HATPase_ATP-bdATP-binding region, ATPase-likeDomain
    IPR009071HMG_box_domHigh mobility group boxDomain
    BlocksIPB002099DNA mismatch repair proteinDNA mismatch repair protein

    Gene Ontology    
    Type Term Evidence Source Pub
    Cellular Component nucleus TAS GOA 8072530
    Molecular Function DNA binding TAS GOA 8072530

    PMS1 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene