Gene content
Symbol	PRAM1 ( by HUGO)
Name	PML-RARA Regulated Adaptor Molecule 1
Category	Oncogene
Alias	PML-RARA Regulated Adaptor Molecule 1 PRAM PRAM-1 PML-RAR PML-RARA Target Gene Encoding An Adaptor Molecule-1 PML-RARA-Regulated Adapter Molecule 1
Cytogenetic band	NCBI: 19p13.2    Ensembl: 19p13.2
Protein information	PRAM_HUMAN Size: 718 amino acids Mass: 79245 Da Subunit: Interacts with SKAP2, LCP2 and DBNL. May interact with LYN. Interacts with NEK6 Tissue specificity: Expressed in peripheral blood leukocytes and bone marrow. Expressed in monocytes, and to a lesser extent in granulocytes and lymphocytes. Not expressed in non hematopoietic tissues except in lung [IMAGE] Custom PCR Arrays for PRAM1 Primer Products: [IMAGE Function: UniProtKB/Swiss-Prot Summary: PRAM_HUMAN, Q96QH2 Function: May be involved in myeloid differentiation. May be involved in integrin signaling in neutrophils. Binds to PtdIns(4)P Similarity: Contains 1 SH3 domain [IMAGE]

Protein Domain/Family
Source	ID	Domain	Name	Type
InterPro	IPR001452	SH3_domain	SH3	Domain
Blocks	IPB001452	SH3 domain signature	SH3 domain signature

PRAM1 cross reference
PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene