Gene content    
RAD54B ( by HUGO)
RAD54 Homolog B (S. Cerevisiae)
Other
RAD54 Homolog B (S. Cerevisiae)
RDH54
DNA Repair And Recombination Protein RAD54B
EC 3.6.4.-
RAD54 Homolog B
EC 3.6.1
NCBI: 8q22.1    Ensembl: 8q22.1
RA54B_HUMANSize: 910 amino acidsMass: 102967 Da

  • Subunit: Interacts with RAD51 through the NH2-terminal domain. Immunoprecipitation experiments show that the interaction is constitutive and not induced by ionizing radiation. The interaction may be indirect
  • Tissue specificity: Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon [IMAGE] Custom PCR Arrays for RAD54B Primer Products: [IMAGE] OriGene qPCR primer pairs and template standards for RAD54B OriGene qSTAR qPCR pri
  • Function:
    UniProtKB/Swiss-Prot Summary: RA54B_HUMAN, Q9Y620 Function: Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group
  • Similarity:
    Belongs to the SNF2/RAD54 helicase family
                          
    Contains 1 helicase ATP-binding domain
                          
    Contains 1 helicase C-terminal domain [IMAGE]

    • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR000330SNF2_NSNF2-relatedDomain
    IPR001650Helicase_CHelicase, C-terminalDomain
    BlocksIPB000330SNF2 related domainSNF2 related domain

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process ATP catabolic process IDA GOA 16428451
    DNA duplex unwinding TAS GOA 10362364
    double-strand break repair via homologous recombination IDA GOA 16428451
    mitotic recombination TAS GOA 10362364
    reciprocal meiotic recombination TAS GOA 10362364
    Molecular Function DNA helicase activity TAS GOA 10362364
    DNA translocase activity IDA GOA 16428451
    RNA helicase activity TAS GOA 10362364

    RAD54B cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene