Gene content  |
| REV3L ( by HUGO) |
| REV3-Like, Polymerase (DNA Directed), Zeta, Catalytic Subunit |
| Tumor suppressor gene |
| REV3-Like Polymerase (DNA Directed) Zeta Catalytic Subunit POLZ REV3 EC 2.7.7.7 DNA polymerase REV3 (Yeast Homolog)-Like Catalytic Subunit Of DNA Polymerase Zeta REV3-Like Catalytic Subunit Of DNA Polymerase Zeta (Yeast) zeta DNA Polymerase Zeta Catalytic Subunit Rev-3 Yeast Homolog-Like (Polymerase DNA Zeta) REV3-like hREV3 Protein Reversionless 3-Like EC 2.7.7 |
| NCBI: 6q21 Ensembl: 6q21 |
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Subunit: Interacts with MAD2L2 6 PDB 3D structures from [IMAGE] and Proteopedia [IMAGE] for REV3L: 3ABD (3D) [IMAGE] 3ABE (3D) [IMAGE] 3VU7 (3D) [IMAGE] 4EXT (3D) [IMAGE] 4GK0 (3D) [IMAGE] 4GK5 (3D) [IMAGE]
Tissue specificity: Ubiquitously expressed [IMAGE] Custom PCR Arrays for REV3L Primer Products: [IMAGE] OriGene qSTAR qPCR primer pairs in human, mouse for REV3L [IMAGE] Pre-validated RT2 qPCR Primer Assay in human, mouse, rat REV3L [IMAGE] QuantiTect SYBR Green Assays in hu
Function: Interacts with MAD2L2 to form the error prone DNA polymerase zeta involved in translesion DNA synthesis Interacts with MAD2L2 to form the error prone DNA polymerase zeta involved in translesion DNA synthesis
Catalytic activity: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Similarity: Belongs to the DNA polymerase type-B family Contains 1 CysA-type zinc finger [IMAGE]
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