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Subunit: Binds GRB7 and PLXNB1. Interacts with UBXD5. Interacts with PLXNA2
Tissue specificity: Mostly expressed in brain and liver [IMAGE] Pathway & Disease-focused RT2 Profiler PCR Arrays including RND1: Notch Signaling Targets in human mouse rat Cardiotoxicity in human mouse rat Primer Products: [IMAGE] OriGene qPCR primer pairs and template stan
Function: UniProtKB/Swiss-Prot Summary: RND1_HUMAN, Q92730 Function: Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments Gene Ontology (GO): 4 molecular function terms: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0003924 GTPase activity NAS 11095956 GO:0005102 receptor binding IPI 19843518 GO:0005515 protein binding IPI 10664463 GO:0005525 GTP binding IEA -- [IMAGE] Find genes that share ontologies with RND1 About GenesLikeMe Animal Models: [IMAGE] inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RND1 [IMAGE] inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RND1 [IMAGE] genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RND1 [IMAGE] genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RND1 miRNA Products: miRTarBase miRNAs that target RND1: hsa-mir-128-3p (MIRT021868) [IMAGE] Block miRNA regulation of human, mouse, rat RND1 using miScript Target Protectors [IMAGE] 2 qRT-PCR Assays for microRNAs that regulate RND1: hsa-miR-199a-5p hsa-miR-199b-5p [IMAGE] SwitchGear 3'UTR luciferase reporter plasmid: RND1 3' UTR sequence Inhib. RNA Products: [IMAGE] OriGene RNAi products in human, mouse, rat for RND1 [IMAGE] Predesigned siRNA for gene silencing in human, mouse, rat RND1 Gene Editing Products: [IMAGE] DNA2.0 Custom Protein Engineering Service for RND1 Clone Products: [IMAGE] OriGene clones in human, mouse for RND1 (see all 7) OriGene ORF clones in mouse, rat for RND1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling [IMAGE] GenScript: all cDNA clones in your preferred vector: RND1 (NM_014470) [IMAGE] Sino Biological Human cDNA Clone for RND1 [IMAGE] DNA2.0 Custom Codon Optimized Gene Synthesis Service for RND1 [IMAGE] Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RND1 [IMAGE] Addgene plasmids for RND1 [IMAGE] Cell Line Products: [IMAGE] GenScript Custom overexpressing Cell Line Services for RND1 [IMAGE] Browse ESI BIO Cell Lines and PureStem Progenitors for RND1 [IMAGE] In Situ Assay Products: [IMAGE] Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RND1
Similarity: Belongs to the small GTPase superfamily. Rho family [IMAGE]
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